Designs for Health B-Supreme, Coenzymated B Vitamin Complex for Energy and Methylation Support, 60 Capsules

Designs for Health B-Supreme Details

Designs for Health B-Supreme is a high-potency B vitamin complex that supplies most of the B vitamins in their coenzymated (active) forms, so the body does not have to phosphorylate them before using them in biochemical reactions. Each vegetable capsule provides 250 mcg of vitamin B12 as methylcobalamin, 200 mcg of folate as [6S]-5-methyltetrahydrofolate, 50 mg of vitamin B6 as pyridoxal 5-phosphate and pyridoxine HCl, and 50 mg of riboflavin including riboflavin-5-phosphate, plus 200 mg of trimethylglycine (TMG) and 30 mg of choline to support methylation. One capsule a day, 60 vegetable capsules per bottle. Made by Designs for Health.

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Quick Facts

Who B-Supreme Is For

• Adults who want a one-a-day B-complex built on active, coenzymated forms
• People looking for methylated B12 and folate rather than cyanocobalamin and folic acid
• Those supporting healthy homocysteine metabolism and methylation (TMG and choline are included)
• Vegans and vegetarians who want to support their B vitamin status
• Anyone wanting a practitioner-grade B-complex in a vegetable capsule

Who this product is NOT for:

• Children — the label dose is for adults
• People taking levodopa or methotrexate, unless their health care practitioner approves — the Canadian technical sheet lists cautions for vitamin B6 with levodopa and folate with methotrexate
• Anyone with upcoming lab tests who has not told their practitioner — biotin can interfere with some diagnostic assays
• Pregnant or breastfeeding women, unless advised by a health care practitioner

Vitamart's Take

B-Supreme is a strong, no-filler B-complex: one capsule covers the full B family in mostly coenzymated forms, with methylcobalamin, 5-MTHF and P5P where they matter most. The added TMG and choline set it apart from basic B-complex formulas by giving extra methylation support in the same capsule. At one capsule a day, the 60-count bottle lasts two months.

How B-Supreme Compares

Coenzymated vs. standard B-complex

Many basic B-complex products use cyanocobalamin, folic acid and pyridoxine HCl, which the body has to convert. B-Supreme supplies methylcobalamin, [6S]-5-MTHF and pyridoxal 5-phosphate directly.

B-Supreme vs. L-5-MTHF

Designs for Health L-5-MTHF is a single-nutrient methylfolate at 1000 mcg per capsule. B-Supreme gives 200 mcg of 5-MTHF alongside the rest of the B vitamins, TMG and choline — a better fit if you want broad B coverage rather than folate alone.

B-Supreme vs. TRUMARK TRU-B

TRUMARK TRU-B is Vitamart's own methylated B-complex in vegetable capsules. Both use active B12 and folate; B-Supreme adds TMG and choline for extra methylation support.

What Is a Coenzymated B-Complex?

• B vitamins act as coenzymes — helpers that enzymes need to turn food into energy and to run methylation
• "Coenzymated" means the vitamin is supplied in the form the body actually uses, such as pyridoxal 5-phosphate for B6 or methylcobalamin for B12
• Methylated folate ([6S]-5-MTHF) and methyl-B12 work together in the methylation cycle that recycles homocysteine
• Trimethylglycine (betaine) and choline are methyl donors that support the same pathway
• B vitamins are water-soluble and not stored in large amounts, so they need regular replenishing

Recommended Purpose

• Supports B vitamin status in the body
• Promotes the optimal intake of essential micronutrients for overall health
• Supports healthy homocysteine metabolism
• May be helpful for individuals following vegan or vegetarian diets

How To Use

• Adults: take 1 capsule per day with a meal, or as directed by your health care practitioner
• Consult a health care practitioner for use beyond 3 months
• Consult a health care practitioner prior to use if you have high cholesterol, heart or kidney problems
• Store in a cool, dry place and keep out of reach of children

Medicinal Ingredients (per capsule)

Non-medicinal ingredients: hypromellose, silicon dioxide, magnesium stearate (vegetable source), stearic acid (vegetable source).

Frequently Asked Questions

Pairs Well With

• Designs for Health Magnesium Glycinate Complex
• Omega 3 Supplements
• Vitamin D Supplements
• Energy Booster Supplements

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Compare Similar Products

• All B Complex Supplements
• TRUMARK TRU-B Methylated B-Complex
• Designs for Health L-5-MTHF
• Methylated Vitamins

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Recommended Use: As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.