• 90 Capsules | Thorne Methyl-Guard Plus

  • Gluten Free Gluten Free
  • Dairy Free Dairy Free
  • Soy Free Soy Free

Thorne Methyl-Guard Plus, 5-MTHF Folate, Methylcobalamin B12, P5P B6 and Betaine for Methylation and Homocysteine Support, 90 Capsules

Thorne Methyl-Guard Plus, 5-MTHF Folate, Methylcobalamin B12, P5P B6 and Betaine for Methylation and Homocysteine Support, 90 Capsules

Size

Want to special order this item?

Request a larger quantity

Request a larger quantity

We'll email you an invoice. Once it's paid we order the stock — it typically reaches our warehouse in 1–2 weeks, then ships to you.

We usually reply within 1–2 business days

    Enjoy secure payments powered by:
  • Visa
  • Mastercard
  • Apple Pay
  • PayPal
  • Google Pay
  • Shop Pay
  • American Express

30-day Return Policy Learn more


  • Gluten Free Gluten Free
  • Dairy Free Dairy Free
  • Soy Free Soy Free

Thorne Methyl-Guard Plus combines 600 mg betaine (TMG) with active Quatrefolic® 5-MTHF folate, methylcobalamin B12, P5P B6 and riboflavin 5'-phosphate to help support healthy homocysteine levels for cardiovascular health, support liver function and help form red blood cells. One capsule daily.

90 Capsules | Thorne Methyl-Guard Plus

Thorne Methyl-Guard Plus, 5-MTHF Folate, Methylcobalamin B12, P5P B6 and Betaine for Methylation and Homocysteine Support, 90 Capsules

by Thorne Research

$77.50 CAD
$77.50 CAD
Sale Sold out
Low Price Guarantee
Low Price Guarantee

If you find a lower price, we'll beat it

Brands You Can Trust
Brands You Can Trust

Quality products you can depend on

Fast Free Shipping
Fast Free Shipping

Canadian orders $79+ ship free

Hassle-Free Returns
Hassle-Free Returns

Not happy? Return it within 30 days

Thorne Methyl-Guard Plus Details

Thorne Methyl-Guard Plus is a methylation support formula from Thorne that brings together the nutrients your body uses to keep homocysteine in a healthy range. Each capsule delivers 600 mg of betaine (trimethylglycine) with active forms of folate, vitamin B12, vitamin B6 and vitamin B2, so the nutrients are ready for the body to use.

Folate is supplied as Quatrefolic® L-5-methyltetrahydrofolate (5-MTHF), vitamin B12 as methylcobalamin, vitamin B6 as pyridoxal 5'-phosphate (P5P) and riboflavin as riboflavin 5'-phosphate. Thorne Methyl-Guard Plus is licensed by Health Canada (NPN 80061614) to help support healthy homocysteine levels for the maintenance of cardiovascular health, help support liver function and help to form red blood cells.

Who Thorne Methyl-Guard Plus Is For

Thorne Methyl-Guard Plus is for adults looking for daily methylation and homocysteine support in one capsule. It suits people who prefer active forms of B vitamins over folic acid and cyanocobalamin, and people following gluten-free, dairy-free or soy-free diets.

Thorne Methyl-Guard Plus Features and Benefits

  • Homocysteine Support for Heart Health: Folate, vitamin B12, vitamin B6 and betaine help support healthy homocysteine levels for the maintenance of cardiovascular health.
  • Active Quatrefolic® 5-MTHF Folate: Provides 1 mg of folate as L-5-methyltetrahydrofolate, the active form of folate.
  • Methylcobalamin Vitamin B12: 1 mg of vitamin B12 in its active methyl form.
  • P5P Vitamin B6 and Active B2: 15 mg of pyridoxal 5'-phosphate and 30 mg of riboflavin 5'-phosphate.
  • 600 mg Betaine (TMG) Methyl Donor: Trimethylglycine supports the methylation cycle alongside folate and B12.
  • Liver and Red Blood Cell Support: Helps support liver function and helps to form red blood cells.
  • One Capsule a Day: 90 capsules per bottle for a 90-day supply.
  • Clean Formula: Made without gluten, dairy, soy, eggs, peanuts, tree nuts, fish or shellfish, in a hypromellose (cellulose) capsule.

Frequently Asked Questions

Product Information

➕ What is Thorne Methyl-Guard Plus?
Thorne Methyl-Guard Plus is a methylation support formula that combines active forms of folate (Quatrefolic® 5-MTHF), vitamin B12 (methylcobalamin), vitamin B6 (pyridoxal 5'-phosphate) and vitamin B2 (riboflavin 5'-phosphate) with 600 mg of betaine (trimethylglycine) in each capsule.
➕ How do I take Thorne Methyl-Guard Plus?
Adults take 1 capsule once daily, or as recommended by a health care practitioner.
➕ How many servings are in a bottle?
Each bottle contains 90 capsules. At 1 capsule per day, one bottle provides 90 servings.
➕ Is Thorne Methyl-Guard Plus licensed by Health Canada?
Yes. Thorne Methyl-Guard Plus is a licensed natural health product with NPN 80061614.
➕ Is Thorne Methyl-Guard Plus gluten free?
Yes. Thorne Methyl-Guard Plus is made without gluten, dairy, soy, eggs, peanuts, tree nuts, fish or shellfish.
➕ Who should talk to a health care practitioner before using it?
Consult a health care practitioner before use if you are pregnant or breastfeeding, or if you have high cholesterol. 5-MTHF supplementation is not recommended at the same time as methotrexate cancer therapy.

Benefits of Ingredients

➕ Why does Methyl-Guard Plus use 5-MTHF instead of folic acid?
5-MTHF (L-5-methyltetrahydrofolate) is the active form of folate the body uses directly. Methyl-Guard Plus provides 1 mg of folate as Quatrefolic® 5-MTHF glucosamine salt, so it does not need to be converted from folic acid first.
➕ What does betaine (TMG) do?
Betaine, also called trimethylglycine, is a methyl donor. Together with folate and vitamin B12 it helps support healthy homocysteine levels for the maintenance of cardiovascular health.
➕ Why are vitamins B2, B6 and B12 included?
Riboflavin, vitamin B6 and vitamin B12 work alongside folate in methylation. In Methyl-Guard Plus they help to form red blood cells and support liver function. All three are provided in their active, coenzyme forms.

Adults: Take 1 Thorne Methyl-Guard Plus capsule once daily, or as recommended by a health care practitioner.

Helps support healthy homocysteine levels for the maintenance of cardiovascular health. Helps to support liver function. Helps to form red blood cells.

Nutrition Facts / Valeur nutritive

Serving Size: 1 capsule
Servings per Container: 90		Amount Per Serving
Betaine (Betaine Anhydrous / Trimethylglycine)600 mg
Riboflavin (Riboflavin 5'-Phosphate Sodium)30 mg
Vitamin B6 (Pyridoxal 5'-Phosphate)15 mg
Folate (L-5-Methyltetrahydrofolic Acid, Glucosamine Salt)†1 mg
Vitamin B12 (Methylcobalamin)1 mg
Non-Medicinal Ingredients: Hypromellose (derived from cellulose) capsule, Calcium Citrate, Calcium Laurate.
† Quatrefolic® is a registered trademark of Gnosis S.p.A.

Additional Ingredients

Hypromellose (derived from cellulose) capsule, Calcium Citrate, Calcium Laurate.

Allergy Information

Free of gluten, dairy, soy, eggs, peanuts, tree nuts, fish and shellfish. Contraindicated in individuals with a history of hypersensitivity to any of the ingredients.

Warnings

If you are pregnant or breastfeeding, consult a health care practitioner prior to use. If you have high cholesterol, consult a health care practitioner prior to use. 5-MTHF supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity. Do not use if security seal is broken. Store tightly sealed in a cool, dry place. Keep out of reach of children.

Thorne Methyl-Guard Plus, 5-MTHF Folate, Methylcobalamin B12, P5P B6 and Betaine for Methylation and Homocysteine Support Customer Reviews