Serrapeptase Supplements

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Serrapeptase is a proteolytic enzyme — an enzyme that breaks down proteins — originally identified from bacteria and now produced for supplements. It’s measured in SU (serrapeptase units) of enzyme activity, with 120,000 SU being the most common high-potency strength. Because it’s an enzyme, how it’s delivered matters: most serrapeptase is enteric-coated or delayed-release so it passes through the stomach intact, and it’s taken on an empty stomach. You’ll find capsules here across a range of potencies from several trusted enzyme brands.

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    What serrapeptase is

    Serrapeptase is a proteolytic enzyme — meaning it breaks down proteins. It was originally identified from a bacterium and is now produced through fermentation for use in supplements. It belongs to the same broad family as other "systemic" enzymes people take, and it's sold as capsules measured by enzyme activity rather than by weight.

    Understanding SU potency

    Serrapeptase is measured in SU (serrapeptase units), which reflect enzyme activity, not milligram weight. Common strengths run 60,000, 90,000, and 120,000 SU, with 120,000 SU being the popular high-potency option. A higher SU number means more enzyme activity per capsule — it's the figure to look at when comparing products, rather than the capsule size.

    Enteric coating and how to take it

    This is the practical part that matters most. Stomach acid degrades enzymes, so good serrapeptase is enteric-coated or delayed-release to protect it until it's past the stomach. It's taken on an empty stomach — typically first thing in the morning or well between meals — so it isn't put to work digesting your food. Follow the timing and dose on the label.

    Serrapeptase vs. nattokinase

    Both are proteolytic enzymes people take systemically, so they often come up together. They're distinct enzymes with different typical uses — if you're weighing one against the other, see our nattokinase collection to compare. Some people take them for different reasons; they are sometimes used together.

    Serrapeptase in Canada

    Serrapeptase sold in Canada carries a Natural Product Number (NPN) from Health Canada and ships from our Ontario warehouse to addresses across Canada.

    Safety and who should be cautious

    Because serrapeptase is a protein-digesting enzyme that may affect blood clotting, it isn't suitable for people taking blood thinners or those with bleeding disorders, and it should be stopped before any surgery. Mild digestive upset or appetite changes are possible. If you're pregnant, breastfeeding, take medication, or manage a health condition, talk to your healthcare provider before using serrapeptase.

    Serrapeptase FAQs