Serrapeptase Supplements

What serrapeptase is

Serrapeptase is a proteolytic enzyme — meaning it breaks down proteins. It was originally identified from a bacterium and is now produced through fermentation for use in supplements. It belongs to the same broad family as other "systemic" enzymes people take, and it's sold as capsules measured by enzyme activity rather than by weight.

Understanding SU potency

Serrapeptase is measured in SU (serrapeptase units), which reflect enzyme activity, not milligram weight. Common strengths run 60,000, 90,000, and 120,000 SU, with 120,000 SU being the popular high-potency option. A higher SU number means more enzyme activity per capsule — it's the figure to look at when comparing products, rather than the capsule size.

Enteric coating and how to take it

This is the practical part that matters most. Stomach acid degrades enzymes, so good serrapeptase is enteric-coated or delayed-release to protect it until it's past the stomach. It's taken on an empty stomach — typically first thing in the morning or well between meals — so it isn't put to work digesting your food. Follow the timing and dose on the label.

Serrapeptase vs. nattokinase

Both are proteolytic enzymes people take systemically, so they often come up together. They're distinct enzymes with different typical uses — if you're weighing one against the other, see our nattokinase collection to compare. Some people take them for different reasons; they are sometimes used together.

Serrapeptase in Canada

Serrapeptase sold in Canada carries a Natural Product Number (NPN) from Health Canada and ships from our Ontario warehouse to addresses across Canada.

Safety and who should be cautious

Because serrapeptase is a protein-digesting enzyme that may affect blood clotting, it isn't suitable for people taking blood thinners or those with bleeding disorders, and it should be stopped before any surgery. Mild digestive upset or appetite changes are possible. If you're pregnant, breastfeeding, take medication, or manage a health condition, talk to your healthcare provider before using serrapeptase.