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Designs for Health SPM Supreme with Omega-3s, Immune System and Inflammatory Response Support, 60 Softgels
Designs for Health SPM Supreme with Omega-3s, Immune System and Inflammatory Response Support, 60 Softgels
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Designs for Health SPM Supreme combines omega-3 fatty acids (EPA & DHA) with specialized pro-resolving mediators (SPMs) to support a healthy inflammatory response and normal recovery. Gluten-free and non-GMO.

Designs for Health SPM Supreme with Omega-3s, Immune System and Inflammatory Response Support, 60 Softgels
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Designs for Health SPM Supreme Details
Designs for Health SPM Supreme is an advanced omega-3 supplement that combines three specialized pro-resolving mediators (SPMs) with EPA and DHA fatty acids to support the body's natural inflammatory response, immune system function and recovery processes. The fish oil comes from anchovy, sardine, mackerel and herring. Gluten-free, dairy-free, soy-free and non-GMO. 60 softgels. Made by Designs for Health.
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Quick Facts
| Key ingredients | Three specialized pro-resolving mediators (SPMs) plus EPA and DHA omega-3s |
| Fish sources | Anchovy, sardine, mackerel and herring oil |
| Format | Softgels, 1 softgel twice daily |
| Size | 60 softgels |
| Animal-sourced ingredients | Fish oil (contains fish) |
| Diet notes | Gluten-free, dairy-free, soy-free, non-GMO |
Who SPM Supreme Is For
- Adults who want to support a healthy inflammatory response
- People supporting normal recovery after exercise or physical stress
- Those who want to maintain healthy tissue repair processes
- Anyone looking to support immune system balance
- People who want to add EPA and DHA if they don't regularly eat fatty fish
Who this product is NOT for:
- Vegetarians and vegans — it is made from fish oil
- Anyone with a fish allergy
- Anyone under 18 — the dose is for adults 18 years and older
- People who mainly want a high-dose EPA/DHA fish oil — see OmegAvail Hi-Po or OmegAvail Ultra
Vitamart's Take
SPM Supreme goes a step beyond regular fish oil. SPMs are compounds the body naturally produces from omega-3 fatty acids such as EPA and DHA, and they help support the body's ability to respond to and resolve inflammatory processes. By combining three SPMs with EPA and DHA in one softgel, Designs for Health targets a balanced inflammatory response, recovery and tissue repair. It is a strong choice for active people and anyone focused on inflammatory balance, at a simple dose of one softgel twice a day.
How SPM Supreme Compares
SPM Supreme vs. regular fish oil
Traditional fish oil provides omega-3 fatty acids like EPA and DHA. SPM Supreme combines EPA and DHA with SPMs, specialized compounds involved in the body's natural inflammatory response pathways.
SPM Supreme vs. OmegAvail Ultra
Designs for Health OmegAvail Ultra is a concentrated EPA and DHA fish oil from Alaska pollock for brain and heart support. SPM Supreme is built around SPMs for inflammatory balance and recovery.
SPM Supreme vs. curcumin
Designs for Health Curcum-Evail uses curcuminoids from turmeric to promote healthy immune and inflammatory responses. SPM Supreme takes an omega-3 based approach.
What Is an SPM?
- SPMs (specialized pro-resolving mediators) are compounds naturally produced in the body from omega-3 fatty acids
- They are derived from EPA and DHA
- SPMs help support the body's natural ability to respond to and resolve inflammatory processes
- SPM Supreme contains three SPMs together with EPA and DHA from fish oil
- EPA supports normal inflammatory balance, and DHA is involved in normal cellular function
How To Use
- Adults 18 years and older: take 1 softgel twice daily, or as recommended by a health-care practitioner
- Store in a cool, dry place
- Keep out of reach of children
Frequently Asked Questions
➕ What is SPM Supreme?
➕ What are SPMs?
➕ How is it different from regular fish oil?
➕ How do I take it?
➕ Where does the fish oil come from?
➕ Is it gluten-free?
Pairs Well With
- Designs for Health Curcum-Evail
- Designs for Health Whole Body Collagen
- Designs for Health Hi-Po Emulsi-D3
- Joint Health
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Compare Similar Products
- All Fish Oil Supplements
- Designs for Health OmegAvail Ultra
- Designs for Health OmegAvail Hi-Po
- Inflammation
About Vitamart
Vitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in quality products you trust at prices you love — no fancy packaging markups, no pushy upsells, just the supplements you need at the lowest prices in Canada. Backed by our Low Price Guarantee: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢. Vitamins Lowest Prices.
Adults 18 years and older: Take 1 Designs for Health SPM Supreme softgel 2 times per day or as recommended by a healthcare practitioner.
Refer to the product label for dosing instructions, age-appropriateness, and relative risk statements. Healthcare practitioners are encouraged to use clinical judgement with case-specific dosing based on intended goals, subject body weight, medical history, and concomitant medication and supplement usage.
Nutrition Facts / Valeur nutritive
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Serving Size: 1 softgel Servings per Container: 60 |
Amount Per Serving |
| Fish Oil (Anchovy, Sardine, Mackerel, and Herring - Whole) | 325 mg |
| Eicosapentaenoic Acid (EPA) | 75 mg |
| Docosahexaenoic Acid (DHA) | 60 mg |
Additional Ingredients
Allergy Information
Contains fish.
Does not contain gluten, dairy, soy protein, or GMOs.Warnings