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Designs for Health IBSynergy, Supports Gut Health, Digestive Comfort and Regular Bowel Movements, 60 Vegetable Capsules
Designs for Health IBSynergy, Supports Gut Health, Digestive Comfort and Regular Bowel Movements, 60 Vegetable Capsules
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Support digestive health, gut comfort, bowel regularity, and healthy gastrointestinal function with Designs for Health IB Synergy. Featuring L-glutamine, perilla extract, 5-HTP, and probiotic yeast support. Vegan, gluten-free, dairy-free, and non-GMO.

Designs for Health IBSynergy, Supports Gut Health, Digestive Comfort and Regular Bowel Movements, 60 Vegetable Capsules
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Designs for Health IBSynergy Details
Designs for Health IBSynergy is a targeted digestive formula that works to maintain regular gut function, motility and normal bowel movements, and supports healthy gut-brain communication. Each vegetable capsule combines 250 mg of L-glutamine, 150 mg of perilla leaf extract, 50 mg of 5-HTP and 4 billion CFU of the probiotic yeast Saccharomyces cerevisiae CNCM I-3856. It targets the enteric nervous system – the "second brain" in the gut that regulates digestion and motility. Vegan, gluten-free, dairy-free, soy-free and non-GMO. 60 capsules. Made by Designs for Health.
Vitamins Lowest Prices | Lowest Price in Canada — Guaranteed | Ships from Ontario across Canada
Quick Facts
| Probiotic per capsule | Saccharomyces cerevisiae (CNCM I-3856) 4 billion CFU |
| L-Glutamine per capsule | 250 mg |
| Perilla leaf extract per capsule | 150 mg (5:1, equivalent to 750 mg dried leaf) |
| 5-HTP per capsule | 50 mg |
| Daily dose | 2 capsules per day with food (adults 18+) |
| Format | Vegetable capsules |
| Size | 60 capsules |
| Diet notes | Vegan, vegetarian, non-GMO; does not contain gluten, dairy or soy |
Who IBSynergy Is For
- Adults who want to support digestive comfort and regular bowel movements
- People supporting healthy gut motility and gastrointestinal function
- Anyone wanting to promote a favourable gut flora with a researched probiotic yeast
- People interested in supporting the gut-brain connection
- Those who want L-glutamine for intestinal lining support in the same formula
Who this product is NOT for:
- Anyone taking antidepressants – the label says do not use, as it contains 5-HTP
- People who are immune-compromised or have scleroderma – the label says do not use
- Pregnant or breastfeeding women should consult a health care practitioner before use
- Anyone under 18 – the label dose is for adults
Vitamart's Take
IBSynergy takes a different angle from a standard probiotic. Instead of only adding bacteria, it combines a well-studied probiotic yeast (S. cerevisiae CNCM I-3856) with L-glutamine for the gut lining, perilla leaf and 5-HTP to support the gut-brain axis. That makes it a good fit for people who want support for regularity and digestive comfort. Because of the 5-HTP, check the cautions carefully if you take any medications.
How IBSynergy Compares
IBSynergy vs. a multi-strain probiotic
Designs for Health ProbioMed 50 delivers 50 billion CFU across 10 bacterial strains. IBSynergy uses a single probiotic yeast plus glutamine, perilla and 5-HTP for gut motility and gut-brain support.
IBSynergy vs. Colon Correct
Designs for Health Colon Correct is aimed at digestive and bowel regularity support. IBSynergy adds a gut-brain focus and a probiotic.
IBSynergy vs. GI-Revive
Designs for Health GI-Revive is a powder for GI lining and regularity support. IBSynergy is a two-capsule daily formula with a probiotic yeast.
What Is Saccharomyces cerevisiae CNCM I-3856?
- Saccharomyces cerevisiae CNCM I-3856 is a specific strain of probiotic yeast (whole-cell brewer's yeast)
- Yeast-based probiotics support a balanced gut environment and could promote a favourable gut flora
- In IBSynergy it is paired with L-glutamine to support the health and integrity of the digestive tract lining
- Perilla leaf and 5-HTP provide targeted support for communication between the digestive and nervous systems
- Take it at least 2–3 hours apart from antifungal agents, which can affect a yeast probiotic
Recommended Purpose
- Supports gastrointestinal health
- Promotes normal gut motility
- Could promote a favourable gut flora
- Supports optimal gut-brain communication
How To Use
- Adults 18 years and older: take 2 capsules per day with food, or as directed by a health care practitioner
- Take at least 2–3 hours before or after taking antifungal agents
- Consult a health care practitioner for use beyond 1 year
- May cause drowsiness – use caution when driving or operating machinery
- Do not use if you are immune-compromised, have scleroderma or take antidepressants
Ingredients (per capsule)
| Saccharomyces cerevisiae (brewer's yeast, whole cell – CNCM I-3856) | 4 billion CFU |
| L-Glutamine | 250 mg |
| Perilla (Perilla frutescens) leaf extract (5:1) (750 mg dried equivalent) | 150 mg |
| L-5-Hydroxytryptophan (L-5-HTP) | 50 mg |
Non-medicinal ingredients: Hypromellose, microcrystalline cellulose, magnesium stearate.
Frequently Asked Questions
➕ What is in IBSynergy?
➕ How do I take it?
➕ Can I take it with antidepressants?
➕ Is the probiotic the same as S. boulardii?
➕ Can I take it with antifungal medication?
➕ Is it vegan?
➕ Will it make me drowsy?
Pairs Well With
- Designs for Health Digestzymes
- Designs for Health DGL Synergy
- Designs for Health Plant Enzyme Digestive Formula
- Glutamine Supplements
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Compare Similar Products
- All Irritable Bowel (IBS)
- Designs for Health ProbioMed 50
- Designs for Health Colon Correct
- Designs for Health GI-Revive
About Vitamart
Vitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in quality products you trust at prices you love — no fancy packaging markups, no pushy upsells, just the supplements you need at the lowest prices in Canada. Backed by our Low Price Guarantee: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢. Vitamins Lowest Prices.
Adults 18 years and older: Take 2 Designs for Health IBSynergy capsules per day with food or as directed by a Healthcare practitioner. Take at least 2-3 hours before or after taking antifungal medications. Consult a healthcare practitioner for use beyond 1 year.
Refer to the product label for dosing instructions, age-appropriateness, and relative risk statements. Healthcare practitioners are encouraged to use clinical judgement with case-specific dosing based on intended goals, subject body weight, medical history, and concomitant medication and supplement usage.
Nutrition Facts / Valeur nutritive
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Serving Size: 1 capsule Servings per Container: 60 |
Amount Per Serving |
| L-5-Hydroxytryptophan (L-5-HTP) | 50 mg |
| L-Glutamine | 250 mg |
| Perilla (Perilla frutescens) Leaf Extract (5:1) (750 mg Dried Equivalent) | 150 mg |
| Saccharomyces cerevisiae (Brewer's Yeast, Whole Cell-CNCM I-3856) | 4.0 billion CFU |
Additional Ingredients
Allergy Information
Warnings
Do not use if you have an immune-compromised condition, if you have scleroderma, or if you are taking anti-depressants. If symptoms of digestive upset occur, worsen, or persist beyond 3 days, or if symptoms persist or worsen, discontinue use and consult a health care practitioner.
Consult a health care practitioner prior to use if you are pregnant or breastfeeding, if you have fever, vomiting, bloody diarrhoea or severe abdominal pain, if you are following a low protein diet, or if you are taking carbidopa or health products with serotonergic activity such as mood balance supplements, cough medication containing dextromethorphan, pain killers or medications for nausea or migraine.
When using this product exercise caution while driving or using machinery, as you may experience drowsiness. Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Some people may experience diarrhea, nausea, vomiting and abdominal pain.