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Thorne Research

Thorne Research 5-MTHF, 60 Capsules

Vitamart Price:  $19.99
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  • Expiry: April 2021NEW! 
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Thorne Research 5-MTHF, 60 Capsules
Thorne Research 5-MTHF, 60 Capsules
$19.99
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Thorne Research 5-MTHF Details

The body’s conversion of synthetic, inactive folic acid is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not be sufficient to meet the body’s needs. Furthermore, up to 60 percent of the Canadian population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.

In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine. Methyl-group donation is vital to many biochemical processes, including the synthesis of serotonin, melatonin, and DNA. 5-MTHF is also involved in production of the catecholamine neurotransmitters (dopamine, norepinephrine, epinephrine) and the production of beneficial nitric oxide in vascular endothelial cells, which promotes healthy blood vessel function.


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Suggested Use

Take 1 Thorne Research 5-MTHF capsule daily or as recommended by a health-care practitioner. Supplement this product with 2.4 mcg/day of Vitamin B12.


Nutrition Facts
Serving Size: 1 Capsule
Servings per Container: 60
Amount Per Serving
Folate (as L-5-Methyltetrahydrofolate*)  1 mg
* Percent daily values are based on a 2000 calorie diet
  † Daily Value not established
Note: Serving Sizes are rounded to the nearest whole serving

Additional Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, L-Leucine, and Silicon Dioxide.

Allergy Information: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Warning: If pregnant, consult your health-care practitioner before using this product. 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.


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