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Overall: 2/10
Effectiveness: 2/10
Value: 2/10
#Reviews: 1

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Onnit Alpha BRAIN, 60 Capsules

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Retail Price: $59.99, You Save $10.02
Vitamart Price:  $49.97
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Onnit Alpha BRAIN Details

NPN: 80041968

Complete Balanced Nootropic

The idea behind Alpha BRAIN was to create a fully-balanced nootropic. Our Alpha GPC and Huperzia Serrata contain nutrients that help your body turn up acetylcholine levels full throttle, while other ingredients assist in elevating neurological components vital to remaining calm, focused, and mentally driven. Our Vinpocetine can help the body deliver oxygen and nutrients to the brain, and the combination of neuro-specific antioxidants, led by our proprietary AC-11®, assists your system in clearing away mental fog and free radicals. The result for our thousands of satisfied customers is an extraordinary combination of lucid dreams, mental drive, focus, and mental acuity.

Onnit Alpha BRAIN Research

Alpha BRAIN, the flagship cognitive enhancing supplement from Onnit Labs, contains a serving of nine natural, well-researched compounds to create an effective and balanced nootropic. Alpha BRAIN aims to elevate focus and mental clarity to help the brain achieve improved cognitive functioning. The ingredients in Alpha BRAIN work on three aspects of enhanced cognition: elevating levels of endogenous neurotransmitters, providing anti-stress compounds, and promoting long-term neuro-protection.

Boosting Neurotransmitters

The human brain is composed of over 10 billion communicating cells, known as neurons, that make over 60 trillion synaptic connections [source]. Neurotransmitters are the chemical messengers that embody the brain's currency of communication. The highly coordinated processes of production and release of these neurotransmitters determine the relative strength or weakness between neighboring neurons. These connections give rise to complex neural circuits, which underlie the apparent phenomena of human cognition.

It is well known that adequate functioning of neurotransmitter synthesis and release is essential to maintain a healthy cognitive state [source]. Self-perceived states, such as attention, mood, focus, and awareness, are highly dependent on the relative levels of neurotransmitter production. Alpha BRAIN aims to elevate the levels of neurological production of the neurotransmitters by providing an abundance of biological neurotransmitter precursors. Specifically, Huperzia Serrata and aGPC are targeted at increasing acetylcholine function, an essential component for learning and memory [source, source]. L-theanine, a compound isolated from green tea, has been shown to mimic the important inhibitory effects of GABA neurotransmission, creating a calm and focused mental state [source]. L-tyrosine is a key intermediary in the biosynthesis of the neurotransmitters dopamine, epinephrine, and norepinephrine, with documented mood elevating properties [source]. Conveniently combined together in the Alpha BRAIN formula, these unique nutrients help provide a strong foundation for the body to enhance endogenous production and maintenance of key neurotransmitters.

Mitigating Stress

Prolonged exposure to environmental stress results in a physiological response that can be harmful to overall health and neurological function. Alpha BRAIN includes a combination of natural anti-stress compounds that have been shown to buffer the brain from stress and provide an overall calming effect. Under the license from Optigenex, Alpha BRAIN is the only nootropic to include AC-11®, a potent extract from Uncaria tomentosa, a plant found in the Amazon rainforest that has been used for hundreds of years as an alimentary herb. AC-11® has independently been proven to promote DNA repair following environmental stress and has documented cognitive benefits [source]. Alpha BRAIN also includes highly concentrated oat straw (Avena sativa), an alleviator of neurological stress and exhaustion, which has been shown to have a positive impact on cognitive performance in healthy subjects [source]. Lastly, Alpha BRAIN contains phosphatidylserine, a phospholipid cell component known to possess ergogenic properties and promote stress tolerance in high performance athletes [source]. Alpha BRAIN aims to decrease our levels of endogenous stress while providing the tools to handle demanding situations, allowing the mind to remain clear and focused.

Targeting Neurological Antioxidants

Oxidative stress, also known as free radical damage, has been implicated in a number of neurological challenges and age-related conditions [source]. Alpha BRAIN includes the highest quality anti-oxidative compounds that have been shown to be beneficial to cognitive function. Pterostilbene, a recently discovered compound isolated from blueberries, has been shown to provide neuroprotection against free radicals [source]. Bacopa Monnieri has been used for centuries in the traditional Ayurvedic medical system of India to improve memory and longevity, possessing both antioxidant and aptogenic properties [source]. Research on the use of Bacopa has shown significant memory improvements and protection again the deposit of harmful neurotoxic molecules [source]. Finally, the inclusion of vinpocetine, a semi-synthetic derivative of the periwinkle plant, promotes blood flow to the brain and possesses potent anti-oxidant properties [source]. These three potent antioxidants are essential to maintaining a healthy, functional nervous system.

Alpha BRAIN Delivers

The Alpha BRAIN formula contains highly effective ingredients that are either cutting edge or have historical use. This combination aims to potentiate the best cognitive performance while maintaining mental clarity and providing long-term neurological health benefits. Data will be published in February from our first pilot study. Full clinical study is ongoing.

Onnit Alpha BRAIN Reviews*

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Product rating*

Product Rating: 2/10

Customer Reviews*

  • 2/10  Side effect

    By Harvey on Tuesday, February 9, 2016 10:49 PM

    Effectiveness: 2/10

    (+) Convenient,Easy To Take
    (-)  Gave Me An Upset Stomach,Gives Me Gas,Hypersensitivity - Allergy

    How did you use it?:Before Bed

    "Took the pills for 5 days. Started noticing gas and stomach pain on the first day. My body also became very sensitive to allergens by the 3rd day. (Sneezing a noticeable amount) + (Itchy)

    * I use to have mild allergies but I haven't had them for 4 years, this product seems to bring them back.

    *Stopped taking the pills and everything is back to normal.

    *Did not notice any cognitive advantages in the 5 days of use. (But to be fare you should use the product for a few weeks)

    *Product made it hard for me to go to sleep.

    **I have not used this product for a month because I did not feel good taking the product. However in order to review I have to check the box that certifies that I have used it for more than a month.

    This review is only biased on 5 days of use Only and is my Own experience. The product might work well for you/others but did not work for me.


    Would you buy this product again? No
    Verified by Vitamart Purchaser

    Was this review helpful?  Yes   No  

*Review Disclaimer: Not everyone has these results. Product experiences vary from person to person. Please use these reviews for information only as they have not been reviewed by a medical professional. Do not substitute the informatioin in the reviews for advice from your physician or other health care professional or any information contained on or in any product label or packaging.

Suggested Use

Adults Only: Take a serving of 2 capsules of Onnit Alpha BRAIN twice a day in morning or early afternoon, preferably with food. Do not exceed recommended dose.

Nutrition Facts
Serving Size: 2 Capsules
Servings per Container: 30
Amount Per Capsule
Huperzine A 62.5 mcg
Cat's Claw [(5:1 Extract, uncaria Tomentosa Stem Bark), equivalent to 875 mg of Cat's Claw] 87.5 mg
L-Theanine 50 mg
Oat [(10:1 Extract, Avena Sativa Ariel Parts),  equivalent to 500 mg of Oat 25 mg
Phosphatidylserine from Phosphatidylserine-Enriched Soy Lecithin 12.5 mg
Vitamin B6 (Pyridoxine Hydrochloride) 2.5 mg
Indian Kino-Tree [(10:1 Extract, Pterocarpus Marsupium Stem Heartwood, standardized to 5% Pterostilbene), equivalent to 3.75 mg of Indian Kino-Tree]  187.5 mcg
Bacopa [(20:1 Extract, Bacopa Monnieri Aerial Parts, standardized to 50% Bacosides A & B), equivalent to 1 g of Bacopa] 25 mg
L-Leucine 15 mg
Choline Alfoscerate (From L- Alpha-Glycerphosphorycholine) 50 mg
L-Tyrosine 125 mg
Gingko (50:1 Extract, Gingko Bilboa Leaf, standardized to 24% Flavonoid Glycosides and 6% Terpene Lactones), equivalent to 2g of Gingko 20 mg
* Percent daily values are based on a 2000 calorie diet
  † Daily Value not established
Note: Serving Sizes are rounded to the nearest whole serving

Additional Ingredients: Cellulose and Magnesium Stearate.

Allergy Information: Some people may experience hypersensitivity (e.g., allergy) in which case, discontinue use.

Warning: Keep out of reach of children. Do not use if pregnant or nursing, or if under age 18. Do not use if you are taking products that affect blood coagulation (e.g., blood thinners, clotting factor replacements, acetylsalicylic acid, ibuprofen, fish oils, Vitamin E) as this may increase the risk of spontaneous bleeding. Consult a health care practitioner prior to use if you are taking prescription medications, if you have celiac disease, fat malabsorption or Vitamin A , D, E deficiency, if you suffer from an immune system disorder, cancer, asthma, or are taking immunosuppressants, if you have severe allergies, if you are following a low protein diet, if you are taking medications for diabetes, high blood pressure, or seizures, or if you have liver disease or Parkinson's disease. Discontinue use if you experience gastrointestinal irritation, dizziness, sweating, muscle cramping/twitching, hyperactivity/anxiety, or decreased appetite. Some people may experience hypersensitivity (e.g., allergy), diarrhea, nausea, slight abdominal cramps, dry mouth, &/or fatigue, in which case, discontinue use.

Product Disclaimer

The products and the claims made about specific products on or through this site have not been evaluated by or the Canadian Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. is not responsible for any statements or claims that various manufacturers make about their products or the general information provided for each product on this website. We cannot be held responsible for typographical errors or product formulation changes. Please consult with your own physician or health care practitioner regarding the suggestions and recommendations made at and especially before using any product sold on this website.