{"product_id":"xymogen-histdao-60-delayed-release-tablets","title":"Xymogen HistDAO, Supports Healthy Histamine Digestion and Digestive Comfort, 60 Delayed Release Tablets","description":"\u003ch2\u003eXymogen HistDAO Details\u003c\/h2\u003e\n\n\u003cp\u003e\u003cstrong\u003eXymogen HistDAO\u003c\/strong\u003e provides DAO (diamine oxidase) — the natural enzyme your body uses to break down histamine from food in the digestive tract — in a delayed-release tablet. For people who are sensitive to histamine-rich foods, supplementing DAO before meals can support healthy histamine digestion and digestive comfort. The delayed-release tablet helps the DAO enzyme reach the small intestine, where dietary histamine is broken down. Xymogen is a US-based premium practitioner brand sold through healthcare professionals. For adults with histamine sensitivity seeking mealtime digestive support. 60 delayed-release tablets.\u003c\/p\u003e\n\n\u003cp class=\"vitamart-trust-strip\"\u003e\u003cstrong\u003eVitamins Lowest Prices\u003c\/strong\u003e  |  \u003ca href=\"https:\/\/www.vitamart.ca\/pages\/low-price-guarantee\"\u003eLowest Price in Canada — Guaranteed\u003c\/a\u003e  |  Ships from Ontario across Canada\u003c\/p\u003e\n\n\u003ch3\u003eQuick Facts\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eKey ingredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDAO (diamine oxidase) enzyme\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWhat it does\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBreaks down histamine from food in the gut\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDelayed-release tablet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommon uses\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHistamine digestion, digestive comfort with histamine-rich foods\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBrand\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eXymogen — US premium practitioner brand\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBottle size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60 delayed-release tablets\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBest taken\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBefore histamine-rich meals\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eWho Xymogen HistDAO Is For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAdults sensitive to histamine-rich foods (aged cheese, wine, fermented foods, cured meats) seeking mealtime support\u003c\/li\u003e\n\u003cli\u003ePeople working with a practitioner on histamine sensitivity who want DAO enzyme support\u003c\/li\u003e\n\u003cli\u003eAdults who experience digestive discomfort after histamine-rich meals\u003c\/li\u003e\n\u003cli\u003ePeople wanting a practitioner-grade DAO supplement with delayed-release delivery\u003c\/li\u003e\n\u003cli\u003eAnyone exploring DAO support as part of a low-histamine dietary approach\u003c\/li\u003e\n\u003cli\u003eAdults wanting premium practitioner-tier histamine digestion support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWho this product is NOT for:\u003c\/strong\u003e If you suspect histamine intolerance or have ongoing symptoms, work with a healthcare practitioner — histamine sensitivity can overlap with other conditions, and proper assessment matters. DAO supplements support the digestion of food-derived histamine; they don't address histamine your body produces internally (such as in allergic reactions), so they are not a treatment for allergies. If you have a true food allergy, DAO is not a substitute for allergy management or emergency medication — consult your practitioner. If you take medications, are pregnant or breastfeeding, consult your practitioner. If you want a broader histamine-sensitivity supplement approach, browse our histamine and immune options.\u003c\/p\u003e\n\n\u003ch3\u003eVitamart's Take\u003c\/h3\u003e\n\u003cp\u003eXymogen HistDAO is a digestive-support supplement for people who are sensitive to histamine-rich foods such as aged cheese, wine, and fermented foods. It provides DAO, a natural enzyme the body uses to break down histamine from food, in delayed-release tablets designed to help the enzyme reach the gut intact.\u003c\/p\u003e\n\n\u003ch3\u003eHow Xymogen HistDAO Compares\u003c\/h3\u003e\n\n\u003ch4\u003eHistDAO vs Antihistamines\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eHistDAO (this product):\u003c\/strong\u003e An enzyme that breaks down histamine from food in the digestive tract — a digestive, food-focused approach.\u003cbr\u003e\n\u003cstrong\u003eAntihistamines:\u003c\/strong\u003e Medications that block histamine receptors in the body — a different mechanism for allergic responses. A fit for allergies, under medical guidance. Different purposes entirely.\u003c\/p\u003e\n\n\u003ch4\u003eHistDAO vs Low-Histamine Diet\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eHistDAO (this product):\u003c\/strong\u003e Supports digestion of dietary histamine, used before histamine-rich meals.\u003cbr\u003e\n\u003cstrong\u003eLow-Histamine Diet:\u003c\/strong\u003e Avoiding histamine-rich foods altogether. A fit as a foundational approach; many people combine a low-histamine diet with DAO for occasional higher-histamine meals.\u003c\/p\u003e\n\n\u003ch4\u003eHistDAO vs Digestive Enzymes\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eHistDAO (this product):\u003c\/strong\u003e Specifically provides DAO to break down histamine.\u003cbr\u003e\n\u003cstrong\u003eDigestive Enzymes:\u003c\/strong\u003e Break down protein, fat, and carbs — general digestion, not histamine-specific. A fit for general meal digestion. Different targets.\u003c\/p\u003e\n\n\u003ch3\u003eWhat Is DAO and Histamine Sensitivity?\u003c\/h3\u003e\n\u003cp\u003eUnderstanding the DAO-histamine connection helps explain how this works:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHistamine in food:\u003c\/strong\u003e Histamine occurs naturally in many foods, especially aged, fermented, and cured ones — aged cheese, wine, sauerkraut, cured meats, and more. This is dietary histamine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDAO's job:\u003c\/strong\u003e Diamine oxidase (DAO) is an enzyme your gut produces to break down histamine from food before it's absorbed. It's your body's natural mealtime histamine processor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLower DAO activity:\u003c\/strong\u003e Some people have reduced DAO activity, which means dietary histamine isn't broken down as efficiently. This can lead to sensitivity and digestive discomfort after histamine-rich foods.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow supplementing helps:\u003c\/strong\u003e Taking DAO before a histamine-rich meal provides extra enzyme to help break down the histamine in that food, supporting digestive comfort.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFood histamine only:\u003c\/strong\u003e Importantly, supplemental DAO works on histamine from food in the gut. It doesn't affect histamine your body produces internally (such as during allergic reactions) — so it's not an allergy treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelayed-release matters:\u003c\/strong\u003e The enzyme needs to reach the small intestine intact. A delayed-release tablet protects the DAO through the stomach so it's active where dietary histamine is processed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eHow To Use\u003c\/h3\u003e\n\u003cp\u003eAdults: Take 1 tablet about 15 minutes before a histamine-rich meal, or as directed by your healthcare practitioner. Because DAO works on food histamine, timing it before the meal is key — it provides the enzyme as the histamine-containing food arrives. Swallow the delayed-release tablet whole.\u003c\/p\u003e\n\u003cp\u003eTalk to a healthcare practitioner before use if you have ongoing symptoms or suspect histamine intolerance (proper assessment matters), have a food allergy (DAO is not a substitute for allergy management or emergency medication), take medications, or are pregnant or breastfeeding. DAO supports food-histamine digestion and is not a treatment for allergies or medical conditions.\u003c\/p\u003e\n\n\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eWhat is DAO?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eDAO (diamine oxidase) is the enzyme your gut naturally produces to break down histamine from food before it's absorbed. Some people have lower DAO activity, leaving them sensitive to histamine-rich foods. Supplementing DAO before meals provides extra enzyme to help break down dietary histamine.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eWhen should I take it?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eTake it about 15 minutes before a histamine-rich meal. Because DAO works on food histamine in the digestive tract, timing it before the meal is key — it provides the enzyme as the histamine-containing food arrives. It's a before-meals supplement, not an all-day one.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eIs it an antihistamine or allergy treatment?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eNo — DAO works on histamine from food in the digestive tract. It doesn't affect histamine your body produces internally (such as in allergic reactions), so it's not an antihistamine or allergy treatment. If you have allergies, work with your practitioner; DAO addresses dietary histamine specifically.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eWhat foods are high in histamine?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eAged, fermented, and cured foods are typically highest — aged cheese, wine, sauerkraut, kombucha, cured and processed meats, and some leftovers. People sensitive to histamine often use DAO before meals containing these foods.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eWhy delayed-release?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eThe DAO enzyme needs to reach the small intestine intact to work on dietary histamine. A delayed-release tablet protects the enzyme through the stomach so it's active where histamine is processed. Swallow it whole rather than crushing it.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003cdetails\u003e\n\u003csummary\u003e➕ \u003cstrong\u003eShould I see a practitioner about histamine sensitivity?\u003c\/strong\u003e\u003c\/summary\u003e\n\u003cdiv\u003eYes, if you have ongoing symptoms or suspect histamine intolerance. Histamine sensitivity can overlap with other conditions, and proper assessment matters. A practitioner can help confirm what's going on and guide an approach that may include diet, DAO, and other support.\u003c\/div\u003e\n\u003c\/details\u003e\n\n\u003ch3\u003ePairs Well With\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/digestive-enzymes\"\u003eDigestive Enzymes\u003c\/a\u003e — general meal digestion alongside histamine support\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/probiotics\"\u003eProbiotics\u003c\/a\u003e — supports overall gut health (choose low-histamine strains if sensitive)\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/products\/aor-quercetin-500-mg\"\u003eAOR Quercetin\u003c\/a\u003e — a bioflavonoid often used in histamine-sensitivity routines\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/immune-support\"\u003eImmune Support Supplements\u003c\/a\u003e — broader immune and histamine wellness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e💡 Subscribe \u0026amp; save up to 10% on every order — never run out of your daily supplements.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003ch3\u003eCompare Similar Products\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/products\/aor-quercetin-500-mg\"\u003eAOR Quercetin\u003c\/a\u003e — Bioflavonoid used in histamine-sensitivity routines.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/digestive-enzymes\"\u003eAll Digestive Enzymes\u003c\/a\u003e — General digestive support.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/digestion-intestinal-and-stomach-health\"\u003eAll Digestive Health Supplements\u003c\/a\u003e — Browse digestive support.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.vitamart.ca\/collections\/immune-support\"\u003eAll Immune Support Supplements\u003c\/a\u003e — Histamine and immune wellness.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAbout Vitamart\u003c\/h3\u003e\n\u003cp\u003eVitamart.ca is Canada's vitamin specialist. We've been selling vitamins and supplements to Canadian families since 2005, shipping from our Ontario warehouse to every province. We believe in \u003cstrong\u003equality products you trust at prices you love\u003c\/strong\u003e — no fancy packaging markups, no pushy upsells, just the vitamins you need at the lowest prices in Canada. Backed by our \u003ca href=\"https:\/\/www.vitamart.ca\/pages\/low-price-guarantee\"\u003eLow Price Guarantee\u003c\/a\u003e: find a lower advertised price at a Canadian competitor and we'll beat it by 1¢.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVitamins Lowest Prices.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Xymogen","offers":[{"title":"60 Delayed Release Tablets","offer_id":45642373791915,"sku":"300111694","price":72.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0621\/4126\/8139\/files\/300111694-xymogen-histdao-60-tablets-min.png?v=1758322691","url":"https:\/\/www.vitamart.ca\/fr\/products\/xymogen-histdao-60-delayed-release-tablets","provider":"Vitamart.ca","version":"1.0","type":"link"}