{"product_id":"bestvitamin-best-fish-oil-2-1-epa-dha","title":"BestVitamin Best Fish Oil 2:1 EPA:DHA 660mg:330mg, Molecularly distilled, pharmaceutical grade, deep sea wild caught, 120 Liquid Softgels","description":"\u003ch2\u003eBestVitamin Best Fish Oil 2:1 (EPA: DHA)\u003c\/h2\u003e\r\n\u003cp\u003eBestVitamin Best Fish Oil 2:1 (EPA: DHA), 120 Softgels is a fish oil of exceptional purity, standardized to the highest concentration. Each softgel provides 990 mg of EPA and DHA in a 2:1 ratio. Omega-3 EPA and DHA support cardiovascular health by promoting healthy triglyceride levels; support joint tissue health by supporting a healthy inflammatory response; and support optimal cognitive health and brain function.\u003c\/p\u003e\r\n\u003cp\u003eBestVitamin Best Fish Oil 2:1 (EPA: DHA), 120 Softgels contains vitamin E as an antioxidant and is hermetically sealed to be secure against the entry of oxygen, ensuring maximum purity, freshness, and stability of the oil through to expiration. Third-party test results guarantee Trident SAP 66:33™ is free of heavy metals, PCBs, pesticides, volatile organics, and other impurities.\u003c\/p\u003e\r\n\u003ch3\u003eWHAT ARE OMEGA‑3 FATTY ACIDS?\u003c\/h3\u003e\r\n\u003cp\u003eOmega-3 fatty acids are long-chain polyunsaturated fatty acids and are considered essential fatty acids because they cannot be synthesized by humans, thus must be obtained from the diet.[1] Fish and other marine life are rich sources of a special class of long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).[1] Plant food and vegetable oils, such as flaxseed, canola, and soybean oil, lack EPA and DHA; however, they do contain the intermediate-chain omega-3 fatty acid α-linolenic acid (ALA). Over the last few decades, numerous health benefits have been attributed to the consumption of the omega-3 fatty acid family, ALA, EPA, and DHA.[1]\u003c\/p\u003e\r\n\u003ch3\u003eTHE OMEGA‑6–TO–OMEGA‑3 BALANCE\u003c\/h3\u003e\r\n\u003cp\u003eThe contemporary Western diet is high in omega-6 fatty acids (omega-6 FAs) and deficient in omega-3 fatty acids (omega-3 FAs).[2] This ultimately leads to an imbalance in the cellular concentration of omega-6–to–omega-3 FAs. Although omega-3 FAs are structurally and functionally distinct from the omega-6 FAs, each is metabolized competitively to form eicosanoids, such as thromboxanes (TX), prostaglandins (PG), and leukotrienes (LT).[2][3] Eicosanoids have hormone-like effects and play an important role in cellular activity. Arachidonic acid (AA), a long-chain omega-6 FA, is the precursor for the harmful eicosanoids that promote inflammation (PGE2, LTB4 ), and stimulate platelet aggregation (TXA2).[3][4] Conversely, EPA is the precursor for the anti-inflammatory and antiaggregatory eicosanoids PGE3, LTB5, and TXA3. By increasing omega-3 FA intake, EPA and DHA are incorporated into cell-membrane phospholipids at the expense of AA, and a balance between the omega-6 and omega-3 FAs is returned, thus promoting healthy cellular structure, fluidity, and activity.[3][4][5]\u003c\/p\u003e\r\n\u003ch3\u003eRECOMMENDED OMEGA‑3 INTAKES\u003c\/h3\u003e\r\n\u003cp\u003eHealthy Adults:[6]\u003cbr\u003eFish oil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1–2 g\/d\u003cbr\u003eCoronary Disease Patients:[7]\u003cbr\u003eEPA+DHA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ~1 g\/d\u003cbr\u003eHypertriglyceridemia:[7]\u003cbr\u003eEPA+DHA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2–4 g\/d\u003cbr\u003eNeurological Disorders:[8]\u003cbr\u003eEPA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1–2 g\/d\u003cbr\u003eInflammatory Disorders (rheumatoid arthritis):[4]\u003cbr\u003eEPA+DHA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 g\/d\u003c\/p\u003e\r\n\u003ch3\u003e\n\u003cbr\u003eSAFETY OF OMEGA‑3 SUPPLEMENTATION\u003c\/h3\u003e\r\n\u003cp\u003eIn 2012 the European Food Safety Authority has advised that a dose of up to 5g\/day of EPA and DHA for a period of 16 weeks in supplement form is considered safe for adults and not associated with any lipid peroxidative changes or adverse events in relation to CVD risk. Omega-3 FAs are thus safe and well-tolerated and can be taken with a wide variety of other supplements.[7][10] Since omega-3 FAs are natural blood thinners, patients taking high dosages of aspirin or medicinal blood thinners should consult\u003cbr\u003etheir health-care professional before use.[10]\u003c\/p\u003e\r\n\u003ch3\u003eNATURAL RATIO AND FORM\u003c\/h3\u003e\r\n\u003cp\u003eThe majority of scientific literature that reports the health benefits of omega-3 FAs is based on fish-oil research in which the oils provide their natural fatty acid ratios and form.[11] Fish oils are most commonly available in a standard 18:12 ratio (18% EPA and 12% DHA) or a concentrated 2:1 ratio and supplied in triglyceride or ethyl ester form. Both triglyceride and ethyl ester forms are highly bioavailable and stable.[11]\u003c\/p\u003e\r\n\u003ch3\u003eOMEGA‑3 FATTY ACIDS AND NUTRITION RESEARCH\u003c\/h3\u003e\r\n\u003ch4\u003eCardiovascular Disease\u003c\/h4\u003e\r\n\u003cp\u003eMain mechanisms through which EPA and DHA reduce the risk of cardiovascular disease (CVD) and sudden death include a reduction in malignant ventricular arrhythmias, suppression of blood clotting and atherosclerosis, improvement in arterial wall tone, and anti-inflammatory effects.[1][12] Intake of 1 g\/day of EPA+DHA in CVD patients can exert antiarrhythmic, hypolipidemic and antithrombotic effects, and at least 500 mg\/day in patients without CVD can have cardioprotective effects.\u003c\/p\u003e","brand":"BestVitamin","offers":[{"title":"Lemon","offer_id":42623030395051,"sku":"22ZZZZ-DiscoSupplier","price":59.97,"currency_code":"CAD","in_stock":false},{"title":"Unflavoured","offer_id":42623030427819,"sku":"SP23202000-DiscoSupplier","price":59.97,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0621\/4126\/8139\/products\/best-fish-oil-unflavoured_c488b328-53ae-4a29-9b5f-773f0f419f43.jpg?v=1716074029","url":"https:\/\/www.vitamart.ca\/fr\/products\/bestvitamin-best-fish-oil-2-1-epa-dha","provider":"Vitamart.ca","version":"1.0","type":"link"}